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Seroquel user wants judge to unseal papers for FDA

A patient who claims the psychiatric drug Seroquel gave him diabetes has asked a judge to unseal maker AstraZeneca's confidential documents about its side effects before U.S. regulators decide whether to approve a version of the drug for millions of new patients.

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AstraZeneca e-mails show debate on Seroquel risks

Plaintiffs' lawyers say AstraZeneca marketing executives for years blocked company scientists trying to raise concerns that schizophrenia drug Seroquel caused weight gain and other problems.

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Attorneys Allege AstraZeneca Hid Info from Patients

Did AstraZeneca hide studies that showed its popular anti-psychotic drug Seroquel could lead to large weight gain and diabetes

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EO Netwerk reportage: AstraZeneca verzwijgt dodelijke bijwerkingen Seroquel

De wetenschap is er zeer duidelijk in, mensen die Seroquel gebruiken hebben aanzienlijk minder kans om te herstellen dan mensen die geen enkele behandeling krijgen. Lange termijn resultaten schizofrenie, bron: Martin Harrow and Thomas Jobe. Factors involved in Outcome and Recovery in Schizophrenia Patients Not on Antipsychotic Medications: A 15-year Multifollow-up Study. The Journal of Nervous and Mental Disease, 195 (2007):406-414. Maar wanneer de patiŽnten psychotherapie geboden zouden worden, dan zijn de cijfers nog veel beter. Een recente studie suggereert dat dan 96% van alle patiŽnten kan herstellen. En dat suggereert het Soteria onderzoek eveneens (90-95% van alle schizofrenie patiŽnten). Medicijnen zijn dus zeker niet 'noodzakelijk'. Wel is het zeer gevaarlijk om te stoppen met Seroquel! Seroquel veroorzaakt namelijk een atrofie van de hersenschors en een vergroting van de basale ganglia. Het medicijn blokkeert dopamine D≤ receptoren in de hersenen en in een reactie daarop maken de hersenen de receptoren gevoeliger zodat iemand biologisch meer gevoelig wordt voor een psychose. Seroquel maakt patiŽnten op die manier chronisch ziek, en wanneer je probeert te stoppen met het medicijn - en in het bijzonder wanneer je abrubt stopt - dan bestaat er een grote kans dat je een zeer heftige psychose krijgt die maanden kan aanhouden, gedurende de tijd dat je hersenen zich moeten herstellen. Dit verklaart ook meteen waarom het zo vaak fout gaat wanneer patiŽnten hun medicatie vergeten in te nemen. Dat komt dus door de veranderingen in de hersenen die veroorzaakt zijn door de medicijnen.


Schizophrenia Drugs (Zyprexa, Risperdal, Seroquel) FDA & Pharma

Leonard Roy Frank, Anti-psychiatry activist and psychiatric survivor discusses the Diagnostic and Statistic Manual of Mental Disorder which is put our by the American Psychiatric Association. He gives an overview of mental disorders and role of psychiatry in controlling the nonconformists in society. Mr. Frank edited the best-selling Random House Webster's Quotationary in 1998 and The History of Shock Treatment in 1978. Active in the psychiatric survivors' movement since 1972, he is a member of MindFreedom International, a coalition of more than 100 grassroots groups working for human rights in psychiatry, and also The Coalition for the Abolition of Electroshock.


AstraZeneca in $355m fraud fine

Anglo-Swedish drug giant AstraZeneca has agreed to pay $354.9m to settle charges it defrauded the US healthcare system.

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Drug firms probed over Iraq cash

GlaxoSmithKline and AstraZeneca have been asked to hand over papers as part of a probe into bribes allegedly paid to Saddam Hussein's former Iraq regime.

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AstraZeneca stroke drug trials' results conflict

Trials of Cerovive, a treatment to limit the damage caused by strokes and one of AstraZeneca's most important experimental drugs, have shown conflicting results in protecting patients, the company said yesterday.

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AstraZeneca Warned by FDA About Misleading Seroquel Marketing Material

The U.S. Food and Drug Administration has sent a warning letter to drug maker AstraZeneca, claiming that some of the company's promotional material for Seroquel contains "false or misleading" information.

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Arkansas Sues AstraZeneca Over Seroquel For Illegal Marketing And Fraud

Arkansas State AG Dustin McDaniel yesterday brought suit against AstraZeneca for illegal marketing and fraud, among other charges, in its sales of Seroquel to various agencies in the State.

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Judge Tosses AstraZeneca Suit Over Blood Thinner

A federal judge has dismissed a securities class action accusing AstraZeneca Plc of misleading its investors about the safety and effectiveness of Exanta, its blood thinner that failed to win the approval of the U.S. Food and Drug Administration.

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